Symbol
Name
ID

Gcgr
glucagon receptor
MGI:99572

Phenotype annotations related to endocrine/exocrine glands

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Diabetes mellitus	Type II diabetes mellitus	Pancreatic alpha-cell hyperplasia	Recurrent pancreatitis	Neoplasm of the pancreas	Increased glucagon level	Glucagonoma
Disease(s) Associated with GCGR	Diabetes mellitus	Type II diabetes mellitus	Pancreatic alpha-cell hyperplasia	Recurrent pancreatitis	Neoplasm of the pancreas	Increased glucagon level	Glucagonoma
Mahvash Disease
type 2 diabetes mellitus

Mouse Phenotypes

abnormal pancreatic alpha cell differentiation

increased pancreatic beta cell proliferation

increased pancreatic alpha cell proliferation

abnormal pancreatic acinar cell morphology

endocrine/exocrine gland phenotype

abnormal pancreatic islet morphology

abnormal pancreatic alpha cell morphology

increased pancreatic alpha cell mass

increased pancreatic alpha cell number

increased pancreatic beta cell mass

enlarged pancreatic islets

pancreatic islet hyperplasia

abnormal exocrine gland morphology

increased pancreas weight

enlarged pancreas

increased pancreas tumor incidence

increased glucagonoma incidence

increased glucagon secretion

Availability

Mouse Genotype

Gcgr^em2Smoc/Gcgr^em2Smoc

Gcgr^tm1Jcp/Gcgr^tm1Jcp

Gcgr^tm1Mjch/Gcgr^tm1Mjch

Gcgr^tm2.1Mjch/Gcgr^tm2.1Mjch
Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺ (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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